Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/237664739?client_source=feed&format=rss
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Saturday, July 14, 2012
World Series Poker deals a hand to Android
Poker fans will be happy to hear that EA has launched World Series Poker on Android today. Texas hold'em, Omaha, and lots of stats and social features are available.
- Enjoy multiple game modes including two different styles of poker with Texas Hold’em and Omaha Poker.
- Play with friends and people around the world at any time via Facebook with anonymous login options coming soon.
- Participate in tournaments to collect virtual WSOP rings and bracelets just like the pros.
- Become a VIP player to track and analyze over 25 statistics including the frequency of raises and the percentage of folds pre-flop.
- Chat in real time with other players and send virtual gifts like energy drinks, sunglasses or even pets like pandas and cobras to friends in-game.
- Earn Pro status to play in exclusive high-stakes tables with other gamers that play like the pros.
- Purchase additional chip stacks and gold in game in addition to winning at tables and through tournaments.
Any poker players in the house interested in giving this a shot? It's free, so all you've got to lose are your chips.
Download: World Series Poker
 |  |
Source: http://feedproxy.google.com/~r/androidcentral/~3/6kOqVVYgSVw/story01.htm
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Friday, July 13, 2012
Provenge prostate cancer treatment ? Profncampbell's Blog
Provenge: A Different Kind of Prostate Cancer Treatment
Provenge? (sipuleucel-T) is a unique treatment option for men who have asymptomatic or minimally symptomatic prostate cancer that has spread (metastasized) and also resisted hormone therapy (also referred to as metastatic castrate resistant or hormone refractory prostate cancer). Before the introduction of Provenge, men with this type of prostate cancer had no promising treatment opportunities.
Studies show that hormone resistant prostate cancer progresses rapidly, therefore prompt treatment is critical. In fact, up to 80% of men with hormone resistant prostate cancer develop metastases, and 46% of men with this form of the disease develop metastases in only two years. (Smith 2005; 2011)
What is Provenge?
Provenge is unlike other prostate cancer treatments because it is a form of immunotherapy, which means it is designed to utilize and work with a man?s immune system to fight prostate cancer. In this sense, Provenge is sometimes referred to as a prostate cancer vaccine, because vaccines are also a form of immunotherapy. However, unlike a true vaccine, Provenge cannot provide immunity against disease.
Provenge is an autologous cellular immunotherapy, which means it uses a man?s own immune cells (autologous) to battle prostate cancer. To accomplish this, a series of carefully orchestrated steps must be followed, with the end result being a drug that is personalized for each patient. Those steps are explained below (?How Provenge Treatment Works?).
How Provenge Differs From Other Prostate Cancer Treatments
The main reason Provenge differs from other treatments for prostate cancer is that it is the only prostate cancer immunotherapy approved by the Food and Drug Administration (FDA) and the first in a new class of therapy to use this approach. Another way to look at Provenge versus other prostate cancer treatments is that while other therapies work against the body? chemotherapy and radiation therapy are toxic and focus on killing cancer cells, while hormone therapy stops production of hormones?Provenge is a positive approach that makes use of the body?s own immune cells (T-cells) which have been activated in a laboratory so they can recognize and battle prostate cancer cells.
Who Can Take Provenge
Dendreon Corporation, makers of Provenge, and The National Comprehensive Care Network recommend Provenge as a first-line treatment for men who meet the following criteria. Let?s take each factor individually.
Asymptomatic or minimally symptomatic prostate cancer. This means a man has no cancer pain or if cancer pain is present, it is not severe enough to require treatment with narcotics.
Cancer has metastasized. The prostate cancer has spread beyond the source tumor in the prostate to other areas of the body, such as the bones.
Resistant to hormone therapy. The patient?s prostate cancer has worsened since undergoing treatment with drugs that stop the production of hormones.
Your healthcare provider can determine if you meet the criteria for treatment with Provenge. Physicians take several other factors under consideration when deciding if a patient is a candidate for Provenge. For example, men who have a lower tumor burden and an otherwise healthy immune system are positive candidates for Provenge. Physicians may also recommend Provenge so men can take advantage of immunotherapy before their disease progresses too far and they are no longer a candidate for treatment with Provenge.
How Provenge Treatment is Prepared
If your healthcare provider decides you are a candidate for Provenge, he or she will not write a prescription and send you off to a pharmacy to fill it. Instead, each dose of Provenge is unique and tailor made for you. Therefore, a series of steps are necessary to create each personalized dose of Provenge using your own blood cells. Here is how the process works.
Your doctor will order a complete blood count to check your blood cell levels.
To make your personalized dose, you must undergo a process called leukapheresis, which involves having your blood drawn either through a vein or through a central venous catheter placed into a large vein near the heart. The blood flows through a tube to a machine where immune cells, platelets, and some red blood cells are collected from the blood sample. The machine then returns the rest of the cells and the blood to the body. This entire process is an outpatient procedure and takes about 3 to 4 hours to complete. You can read, rest, listen to music, or watch a movie during the procedure.
The collected immune cells are sent to a facility where they are activated with a recombinant antigen, which is designed to prompt the immune cells (T-cells) to look for and attack prostate cancer cells. Within 2 to 3 days, the completed personalized dose is then shipped to your doctor or infusion location.
The activated immune cells?your personalized Provenge dose?is given by infusion within about three days of the leukapheresis procedure. The infusion process takes about 2 hours: 1/2 hour before the infusion, you will be given acetaminophen or an antihistamine to help reduce the possibility of side effects associated with the infusion. After the one-hour infusion, you will be observed to be sure there are no adverse reactions to treatment.
Treatment with Provenge involves three infusions, so you must undergo a second leukapheresis procedure two weeks after the first one, and then a third leukaphersis two weeks after the second one. Each leukapheresis is followed by infusion of the personalized dose of Provenge within three days of the collection process.
To recap: A treatment course with Provenge involves three leukapheresis procedures, each of which is followed within 3 days by an infusion of Provenge. The entire treatment course takes 5 weeks. Because each personalized dose of Provenge has a short shelf life, men who miss an infusion appointment will need to undergo another leukapheresis so clinicians can prepare another dose of Provenge.
How to Prepare for Provenge Treatment
If you and your doctor have decided you will undergo Provenge treatment, be sure to tell your healthcare provider about any medical problems you have, including heart problems, lung disorders, and any history of stroke. Also tell him or her about any medications (both prescription and over-the-counter), vitamins, and other supplements you use.
To prepare for the leukapheresis procedure, it is helpful to follow these tips:
Drink more water than you normally do to stay well hydrated
Do not drink any caffeinated beverages on the day of your leukapheresis procedures
Wear comfortable clothing, including sleeves that can be easily raised above the elbow
Eat a breakfast that contains calcium-rich foods, such as almonds, blueberries, bananas, yogurt, and calcium-enriched orange juice or cereal
Ask someone to drive you home after the procedure. Many men feel fatigued after leukapheresis.
How Provenge Affects PSA
Doctors typically use the prostate-specific antigen (PSA) test to monitor the progression of prostate cancer and the effects of treatment. Men who take Provenge should know that even if they do not see an improvement in PSA levels, this does not mean Provenge is not working. Provenge can be effective regardless of any changes reflected in PSA levels.
Benefits of Provenge
The goal and primary benefit of Provenge treatment is to help men with prostate cancer live longer. In a clinical study involving 512 men, Provenge reduced the risk of death in men by 22.5%. More specifically, the median survival for the 341 men who took Provenge was 4.1 months longer than that of the 171 men in the placebo group (25.8 months compared with 21.7 months). (Kantoff) In addition, data from Dendreon Corporation note that at three years, 37.8% more patients treated with Provenge were alive when compared with controls. (Dendron)
Another benefit of Provenge treatment is that men who use Provenge can then go on to use other prostate cancer therapies. In fact, because Provenge stimulates the immune system, men who undergo this immunotherapy are often in better condition to handle immunosuppressive therapies, such as chemotherapy.
Side Effects of Provenge
The most common side effects of Provenge treatment, occurring in at least 15% of patients, are back pain, chills, fatigue, fever, headache, joint ache, and nausea. Side effects are generally not severe enough to cause men to stop treatment. In one study, less than 1.5% of men who took Provenge stopped treatment because of side effects.
Infrequently, Provenge can cause serious reactions, including stroke or severe infusion reactions within one day of infusion, which have been shown in 3.5% of patients. Severe infusion reactions may include breathing problems (reduced oxygen level, shortness of breath, wheezing), chills, dizziness, fatigue, fever, headache, high blood pressure, muscle ache, nausea, vomiting, and weakness.
Men who take Provenge should contact their doctor if they experience any of the mentioned side effects as well as any symptoms not listed that concern them.
Provenge vs Zytiga
Where to Find Provenge
Provenge providers are available around the country. If you are interested in learning more about Provenge, consult your healthcare provider. If you doctor or local hospital cannot provide you with information or access to Provenge, you can locate Provenge providers by visiting the Provenge website:
Frequently Asked Questions
Q: I don?t have health insurance. Can I still get treatment with Provenge?
Dendreon, the pharmaceutical company that makes Provenge, sponsors a program that provides Provenge without cost to men without health insurance who meet their eligibility requirements. Dendreon has also issued grants to independent foundations that provide financial assistance and other types of support (e.g., assistance with co-pays, deductibles, co-insurance, and travel-related treatment costs) to men who have prostate cancer. For information on both of these programs, call 1-877-336-3736.
Q: Is Provenge a vaccine?
Technically, no. Although Provenge is a type of immunotherapy, as are vaccines, Provenge does not provide immunity against prostate cancer. However, it does enlist the body?s immune cells (T-cells) in the fight against prostate cancer.
Q: Can you get just one treatment of Provenge instead of three?
No, it is necessary to get all three infusions of Provenge for the treatment to be effective.
Q: There are no doctors or hospitals in my area that offer Provenge. Where should I go?
The Provenge website offers a search feature to find Provenge providers around the country. Just type in your zip code and you will be given a list of providers within a certain mile radius.
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Source: http://profncampbell.wordpress.com/2012/07/13/provenge-prostate-cancer-treatment/
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NCAA president Mark Emmert
Guest interviews are usually available online within 24 hours of broadcast.
Tavis talks sports with the NCAA president, including a discussion on the potential fallout from the investigation into the Penn State scandal.
In 2010, Mark Emmert became the fifth president of the NCAA. He previously spent some 30 years in administrative and academic positions at various universities, including president at his alma mater, the University of Washington, and chancellor of Louisiana State. He's written extensively on higher education and public administration and is a member of the Higher Education Working Group on Global Issues as part of the Council on Foreign Relations. He also served on the National Security Higher Education Advisory Board. Emmert holds both a master?s degree and a Ph.D. in public administration.
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Obama spends nearly $100 million on campaign ads
President Barack Obama speaks at a campaign event at Green Run High School in Virginia Beach, Va., Friday, July 13, 2012. Obama is spending the day in Virginia campaigning. (AP Photo/Susan Walsh)
President Barack Obama speaks at a campaign event at Green Run High School in Virginia Beach, Va., Friday, July 13, 2012. Obama is spending the day in Virginia campaigning. (AP Photo/Susan Walsh)
President Barack Obama gestures during a campaign stop at Green Run High School in Virginia Beach, Va., Friday, July 13, 2012. ( AP Photo/Steve Helber)
FILE - In this June 28, 2012 file photo, Republican presidential candidate Mitt Romney speaks about the Supreme Court ruling on health care in Washington. Worried about the economy? The rising cost of health insurance? The burgeoning federal debt? Yup, the presidential candidates have a bullet point for that. But despite Republican Mitt Romney's 59-point jobs plans, President Barack Obama's 64-page blueprint for change and both candidates' lofty policy speeches, voters still sense something's missing. (AP Photo/Charles Dharapak, File)
WASHINGTON (AP) ? President Barack Obama's campaign has spent nearly $100 million on television commercials in selected battleground states so far, unleashing a sustained early barrage designed to create lasting, negative impressions of Republican Mitt Romney before he and his allies ramp up for the fall.
In a reflection of campaign strategy, more than one-fifth of the president's ad spending has been in Ohio, a state that looms as a must-win for Romney more so than for Obama. Florida ranks second and Virginia third, according to organizations that track media spending and other sources.
About three-quarters of the president's advertising has been critical of Romney as Obama struggles to turn the election into a choice between him and his rival, rather than a referendum on his own handling of the weak economy. Obama's television ad spending dwarfs the Romney campaign's so far by a margin of 4-1 or more. It is at rough parity with the Republican challenger and several outside GOP-led organizations combined. They appear positioned to outspend the president and his allies this fall, perhaps heavily.
The latest attack ad, which began airing Friday, accuses the Republican of favoring a 25 percent tax cut for millionaires, tax breaks for oil companies and corporations that move jobs overseas and a tax increase for working families. By contrast, it says, the president wants "the wealthy to pay a little more so the middle class pays less."
Democrats and even some Republicans agree the effort to cast Romney as an unfit steward for the economy shows sign of making some headway. Yet GOP strategists hasten to add that the former Massachusetts governor has ample time to counter, particularly with recent signs of a struggling economy and the fall campaign yet to begin.
"Despite all of the negative advertising from the Obama campaign, polling numbers are exactly where they were before they started this onslaught," the Romney campaign said in a memo distributed this week, referring to a rolling average of polls.
Yet Romney released a scathing ad on Thursday designed to respond to some of Obama's charges, the sort of rebuttal that often can signal concern that an attack is hitting home. In 2008, "candidate Obama lied about Hillary Clinton," the ad said, adding there was no truth to the charges that Romney was associated with companies that outsourced jobs.
Some surveys suggest shifts in the electoral landscape. A recent poll by Pew Research Center for the People and the Press found that Romney has lost ground in the past month on the question of which candidate was better able to improve the economy.
"They wanted to define Romney before he could define himself, and by every indication they're doing a very effective job of that" said Jim Jordan, a Democratic strategist who was campaign manager for Democratic presidential candidate John Kerry in 2004.
According to strategists in both parties, focus groups with voters indicate the public knows relatively little about Romney's background, making the subject generally fertile territory for anyone trying to create an impression.
Romney has twice run for president. But even in this year's Republican primaries, his own campaign spent less money on television ads than Restore Our Future, a superPAC that aided him. Most of the outside group's efforts consisted of attacks on Romney's GOP rivals, rather than testimonials to his own background and character.
While outside groups make a difference, "what campaigns said about the candidates is the most important thing" in a race, said Terry Nelson, a Republican strategist who had a senior position in President George W. Bush's re-election campaign.
Another Republican strategist, speaking on condition of anonymity to avoid offending the campaign, said Obama's commercials attacking Romney are quickly defining him and the strategy is effective.
But Carl Forti, one of the strategists involved with Restore Our Future, said Obama's strategy is more defensive than it might appear.
"I don't think he's got a choice. He has to try to change the dynamic now, but the polling indicates it's not working. He doesn't appear to be making any headway in the polls," he said.
There is no dispute about the intensity of the general election ad wars, which began in April with Rick Santorum's withdrawal from the race for the Republican nomination.
"There are more advertisers in fewer markets, spending more money and advertising at a higher frequency than in previous elections," said Elizabeth Wilner, vice president of Kantar Media/CMAG, which monitors advertising.
Wilner said viewers in Columbus, Ohio, "are seeing more ads right now than they were seeing in September of 2008," a period when campaigns traditionally ramp up for the fall. In Iowa, more money has been spent on television ads per electoral vote than in all of 2008, she added.
Obama's campaign has launched four commercials this month, including the attack ad that began during the day.
Two others accuse Romney of having ties to companies that outsource U.S. jobs to low-wage countries overseas. The final one says the former governor supported a law to ban all abortions, including in cases of rape and incest, and wants to end federal funding for Planned Parenthood.
Ads in Ohio, Florida and Virginia account for roughly half of the Obama's campaign ad spending, according to records maintained by groups that track spending and other sources. No Republican has ever been elected president without winning Ohio, and Romney's chances of a victory would be all but extinguished if the president wins either of the two other states.
The Obama campaign also has advertised in Colorado, Iowa, Nevada, New Hampshire, North Carolina and Pennsylvania, on both broadcast and local cable. In some of those states, it has run Spanish-language commercials.
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ijdh: RT @AmberLyon: 7,000 ppl died from @cholera in #haiti since the earthquake, rts groups say UN troops responsible http://t.co/0IKQqwOu #u ...
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Source: http://twitter.com/ijdh/statuses/223779922093686784
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Obama talks up middle class in video to NAACP
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Source: http://news.yahoo.com/obama-talks-middle-class-video-naacp-151139349.html
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